Which enzyme is responsible for converting GTP to cGMP?

Study for the SLCC Physiology Exam 1. Engage with multiple choice questions and flashcards designed to enhance learning and comprehension, complete with hints and detailed explanations. Prepare thoroughly for your examination!

Multiple Choice

Which enzyme is responsible for converting GTP to cGMP?

Explanation:
The enzyme responsible for converting GTP to cGMP is guanylate cyclase. Guanylate cyclase catalyzes the conversion of guanosine triphosphate (GTP) into cyclic guanosine monophosphate (cGMP), which acts as a secondary messenger in various signaling pathways within the cell. This process is significant in regulating various physiological functions, including vasodilation and neurotransmission. cGMP serves as a crucial signaling molecule that can activate protein kinases and influence numerous cellular actions. In contrast, adenylate cyclase primarily converts ATP to cyclic adenosine monophosphate (cAMP), phospholipase C is involved in the production of inositol trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate, and protein kinase G is a downstream effector activated by cGMP rather than an enzyme that converts GTP to cGMP. Thus, guanylate cyclase is the specific enzyme that fulfills the role of producing cGMP from GTP.

The enzyme responsible for converting GTP to cGMP is guanylate cyclase. Guanylate cyclase catalyzes the conversion of guanosine triphosphate (GTP) into cyclic guanosine monophosphate (cGMP), which acts as a secondary messenger in various signaling pathways within the cell.

This process is significant in regulating various physiological functions, including vasodilation and neurotransmission. cGMP serves as a crucial signaling molecule that can activate protein kinases and influence numerous cellular actions.

In contrast, adenylate cyclase primarily converts ATP to cyclic adenosine monophosphate (cAMP), phospholipase C is involved in the production of inositol trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate, and protein kinase G is a downstream effector activated by cGMP rather than an enzyme that converts GTP to cGMP. Thus, guanylate cyclase is the specific enzyme that fulfills the role of producing cGMP from GTP.

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