Which organ is primarily responsible for detoxification in the body?

• A. Kidney
• B. Liver
• C. Stomach
• D. Lung

Answer: (B)

The liver is primarily responsible for detoxification in the body due to its essential role in metabolic processes. It functions by converting harmful substances into less toxic forms, which can then be eliminated from the body. This includes the metabolism of drugs, alcohol, and various toxins, allowing for their safe passage out of the body through bile or urine.

The liver contains specialized cells, known as hepatocytes, that carry out these detoxification processes. These cells are equipped with enzyme systems, such as cytochrome P450 enzymes, which metabolize drugs and toxins, converting them to water-soluble forms that can be excreted.

In contrast, while the kidneys play a significant role in filtering blood and removing waste products through urine, they primarily manage waste excretion rather than detoxification. The stomach is involved in the digestion of food but does not significantly contribute to detoxification. The lungs also have a role in detoxification by excreting volatile substances or gases, but they do not perform the broad range of detoxification functions that the liver does. Therefore, the liver's multifaceted detoxification capabilities make it the primary organ responsible for this critical function in the body.